CLINICAL CORNER

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VITAMINS E AND C DO NOT PREVENT CATARACTS. In a randomized, double-masked, placebo-controlled trial, 11,545 apparently healthy male physicians aged 50 and older without a diagnosis of cataracts received vitamin E or placebo on alternate days and vitamin C or placebo daily. After eight years, it was concluded that long-term alternate-daily use of 400 IU of vitamin E and daily use of 500mg of vitamin C had no notable beneficial or harmful effect on the risk of age-related cataract.

GLAUCOMA PATIENTS AT RISK FOR OTHER SERIOUS CONDITIONS. Open-angle glaucoma (OAG) patients were more likely found to have selected health disorders, many of which can be life threatening or affect quality of life, over individuals without OAG. More than half of the 76,673 OAG participants had hypertension and more than 30% had hyperlipidemia or diabetes. Other conditions including systemic lupus erythematosus, hypothyroidism, fluid and electrolyte disorders, depression, and psychosis were also significantly higher for OAG patients than subjects without glaucoma.

PROTECTION AGAINST AMD WITH FISH/ SHELLFISH. The Salisbury Eye Evaluation Study looked at the relationship between fish and shellfish consumption and age-related macular degeneration (AMD) in a random sample of 2,520 Salisbury, MD, residents aged 65 to 84. Those with advanced AMD were significantly less likely to eat one serving of fish/shellfish high in omega-3 fatty acids in a week than healthy controls, suggesting fish/shellfish intake has a protective effect against advanced AMD. Intake of crabs and oysters weren’t related to AMD status.

ACUPUNCTURE FOR AMBLYOPIA TREATMENT. In a single-center randomized controlled trial, 88 children (aged 7 to 12 ) with an amblyopic eye who had a best spectacle-corrected visual acuity of 0.3 to 0.8 logMAR received two hours of patching of the sound eye daily or five sessions of acupuncture weekly. Acupuncture produced equivalent treatment effects for anisometropic amblyopia compared with patching and was statistically superior.

HEALTHY LIFESTYLES REDUCE AMD RISK. The relationship between the prevalence of AMD and the lifestyle behaviors of diet, smoking, and physical activity was investigated in 1,313 women (aged 55 to 74) from the Carotenoids in Age-Related Eye Disease Study. It was found that modifying these lifestyles might reduce risk for early AMD as much as threefold, lowering the risk for advanced AMD in a person’s lifetime.

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